Jul 24, 2025
THIS WEBSITE DOES NOT PROVIDE MEDICAL ADVICE. The content included on this website is for informational and educational purposes only. Always consult with your healthcare provider regarding any medical condition and before starting any healthcare or medication regimen.
When treating ADHD, stimulant medications are often a key part of a broader management plan. Two options sometimes discussed are Desoxyn and Adderall. While both are classified as stimulants, they differ in their chemical composition, how they’re prescribed, and who they may be suitable for.
This article compares Desoxyn and Adderall in terms of how they work, how they’re taken, and what side effects may occur. You’ll also learn about potential cost-saving options, including using a CareCard prescription discount card—accepted at over 80,000 pharmacies with no insurance or membership required.
Both Desoxyn and Adderall are approved to treat attention-deficit hyperactivity disorder (ADHD). Adderall is also approved for narcolepsy. These medications may help manage symptoms like inattention, impulsivity, and hyperactivity. In some cases, they are used after other treatments have not been effective.
Both medications affect certain neurotransmitters in the brain, including dopamine and norepinephrine. This action may support improved focus, attention, and behavioral regulation. Stimulants are often prescribed as part of a treatment plan that may also include behavioral therapy and lifestyle strategies.
Desoxyn contains methamphetamine hydrochloride, a stimulant that may be used in cases where other ADHD medications have not provided sufficient symptom control. It is generally considered when other options have not worked or have caused side effects that are difficult to manage.
Desoxyn may help reduce core ADHD symptoms in individuals who haven’t responded well to other stimulant options. It is not usually prescribed as a first-line treatment but may offer symptom relief in select cases under close medical supervision.
Typically begins working within 30 to 60 minutes
Duration of action may last around 4 to 6 hours
Available in immediate-release tablet form
Usually dosed once or twice per day, based on provider guidance
Desoxyn may cause:
Decreased appetite
Trouble sleeping
Increased heart rate or blood pressure
Nervousness or irritability
Headache or dry mouth
Desoxyn is a Schedule II controlled substance and should be prescribed and monitored with care.
Adderall contains a mixture of amphetamine salts. It is one of the most commonly prescribed medications for ADHD and may be considered for both children and adults. It comes in both immediate-release and extended-release versions, providing flexibility based on treatment needs.
Adderall has been prescribed for many years and may support improvements in attention, concentration, and impulse control. It is considered effective for many patients, though individual responses can vary.
Immediate-release: lasts around 4 to 6 hours
Extended-release (Adderall XR): may last up to 12 hours
Available in tablet (IR) and capsule (XR) form
Dosing is typically once or multiple times daily depending on the formulation
Adderall may cause:
Loss of appetite
Insomnia
Increased anxiety or restlessness
Stomach discomfort
Elevated heart rate or blood pressure
As with Desoxyn, Adderall is a Schedule II controlled substance and should be used only under a healthcare provider’s supervision.
Desoxyn is based on methamphetamine, while Adderall contains a combination of amphetamine salts. These chemical differences may result in different responses and tolerability for some individuals.
Desoxyn is typically considered after other ADHD treatments have been tried. Adderall is more commonly used and is often a first-line option.
Adderall is available in both short- and extended-release versions. Desoxyn is only available in an immediate-release form.
Both medications are available in generic form. Pricing may vary, and savings may be available through tools like a CareCard prescription discount card.
Past response to stimulant medications
Potential side effects
Duration of symptom coverage needed
Coexisting medical conditions
Insurance coverage and cost
Age and dosage form preference
Desoxyn and Adderall are both stimulant medications used to treat ADHD, but they differ in formulation, availability, and how they are typically prescribed. Choosing the best option depends on a range of personal and medical factors. If prescribed either medication, you may be able to save at the pharmacy using a CareCard prescription discount card, accepted at more than 80,000 pharmacies with no insurance required.
1. Are Desoxyn and Adderall the same? No. Desoxyn contains methamphetamine, while Adderall contains a mix of amphetamine salts. Both are stimulants used to treat ADHD, but they differ in formulation and how they’re typically prescribed.
2. Which is stronger: Desoxyn or Adderall? That depends on the individual. Desoxyn is sometimes used when other stimulants like Adderall haven’t worked well, but strength and effectiveness vary by person.
3. Can I switch from Adderall to Desoxyn? Switching medications should always be done under medical supervision. Your provider may consider Desoxyn if other ADHD medications haven’t been effective.
4. Is Desoxyn commonly prescribed? Desoxyn is not commonly prescribed. It’s usually reserved for cases where other stimulant medications have not provided sufficient results or have caused side effects.
5. How can I save on Desoxyn or Adderall? You can compare prices and potentially save with a CareCard prescription discount card, which works at over 80,000 pharmacies nationwide.