Nov 24, 2025

Azstarys: Dosage, Usage, and Important Information
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Azstarys is a prescription medication used primarily to treat attention deficit hyperactivity disorder (ADHD) in children and adults. It combines two active ingredients, serdexmethylphenidate and dexmethylphenidate, which work as stimulants to help improve focus and attention, and control impulsivity. This article will cover the recommended dosage for Azstarys, how to take it, possible side effects, and important safety information.
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Azstarys is a brand-name medication available in the form of an oral capsule. It’s currently not available in a generic version, meaning if you are prescribed Azstarys, you will receive the brand-name drug.
Before taking Azstarys, it’s crucial to understand its boxed warning, the most serious warning issued by the FDA. The medication carries a risk of misuse and addiction, which is common among stimulant drugs. This means it should be taken exactly as prescribed by your doctor to avoid dependency or other serious issues.
Azstarys comes as an oral capsule that you take by mouth, and it’s available in the following strengths:
26.1 mg/5.2 mg
39.2 mg/7.8 mg
52.3 mg/10.4 mg
The strengths represent the amounts of serdexmethylphenidate and dexmethylphenidate in the capsule. These two active ingredients work together to manage ADHD symptoms throughout the day.
The appropriate dosage of Azstarys will vary depending on your age, response to the medication, and the specific condition being treated. Always follow the dosage instructions provided by your healthcare provider. Below is a general guideline based on manufacturer recommendations.
Starting dosage: 39.2 mg/7.8 mg, taken once daily in the morning
Maintenance dosage: 52.3 mg/10.4 mg, taken once daily in the morning
Maximum dosage: 52.3 mg/10.4 mg, taken once daily in the morning
For children 6 years and older, the following guidelines apply:
Starting dosage: 39.2 mg/7.8 mg, taken once daily in the morning
Maintenance dosage: 26.1 mg/5.2 mg to 52.3 mg/10.4 mg, depending on how the child responds
Maximum dosage: 52.3 mg/10.4 mg, taken once daily in the morning
It’s important to note that Azstarys is generally not prescribed to children under 6 years of age. Doctors typically start with a lower dose for children between 6 and 17 years and gradually adjust it based on the child’s response.
Doctors may adjust the dosage of Azstarys depending on several factors:
Severity of ADHD symptoms
Age of the person taking it
Presence of other health conditions
Response to the medication over time
Azstarys should be taken once daily in the morning, as taking it later in the day may cause difficulty sleeping. Always follow the dosing instructions given by your healthcare provider, as they may adjust your regimen based on your individual needs.
Swallow the capsule whole with water. If swallowing capsules is difficult, you can open the capsule and mix the contents with 2 tablespoons of applesauce or 2 ounces of water. Consume the entire mixture immediately or within 10 minutes of preparation—do not store it for later.
If you have trouble swallowing pills in general, try taking a sip of water first, placing the capsule on your tongue, and then drinking more water to help it go down smoothly.
If you forget to take your dose of Azstarys, contact your healthcare provider for advice. They may instruct you to take the missed dose or skip it and resume your regular schedule. Avoid taking a double dose to make up for the missed one. Missing doses consistently can reduce the effectiveness of the medication, so consider setting reminders or using a pillbox to help you stay on track.
Like all medications, Azstarys can cause side effects. While not everyone will experience side effects, knowing what to look out for is crucial.
Loss of appetite
Weight loss
Insomnia
Nervousness
Headache
Nausea
If these side effects become severe or bothersome, contact your doctor.
Heart problems (chest pain, shortness of breath, or fainting)
Severe mood changes (aggression, depression, or suicidal thoughts)
Allergic reactions (rash, swelling, or trouble breathing)
If you experience any of these more severe side effects, seek medical help immediately.
Before starting Azstarys, discuss your medical history with your doctor, particularly if you have a history of:
Heart disease
High blood pressure
Mental health disorders (such as anxiety, bipolar disorder, or depression)
Substance use disorder
Seizures
Stimulant medications like Azstarys can sometimes increase blood pressure and heart rate, so regular monitoring is recommended, especially for those with preexisting heart conditions.
Azstarys can interact with other medications, which may affect how it works or increase your risk for side effects. Be sure to tell your doctor about all medicines you’re taking, including:
Antidepressants (such as MAO inhibitors)
Blood pressure medications
Other stimulant medications for ADHD
Avoid alcohol while taking Azstarys, as it can increase certain side effects.
To save on Azstarys, consider comparing prices at different pharmacies, as costs vary. Many pharmacies accept prescription discount cards like CareCard, which can significantly reduce your medication's price.
Additionally, check for manufacturer savings programs or coupons for Azstarys that may be available. These programs often provide discounts. If your insurance doesn’t cover Azstarys, looking into generic or alternative options with your healthcare provider could also help make treatment more affordable.
Azstarys is an effective treatment for ADHD in both children and adults, offering long-lasting symptom control with a convenient once-daily dosing schedule. While it carries a boxed warning for the risk of misuse and addiction, it remains a valuable option when used as prescribed. Always follow your healthcare provider’s guidance regarding dosage and usage to maximize benefits and minimize risks.
Here are some commonly asked questions about Azstarys and its dosage:
How Does Azstarys Compare to Adderall and Vyvanse?
Azstarys, Adderall, and Vyvanse are all stimulant medications used to treat ADHD, but they differ in their active ingredients, dosage forms, and how they are metabolized. Each drug is prescribed based on individual needs, so following your doctor’s recommendations is essential.
Can I Take Azstarys Long Term?
Yes, Azstarys is generally prescribed as a long-term treatment for ADHD as long as it remains effective and safe for those taking it. Consult your doctor regularly to evaluate its continued use.
What Should I Do if I Miss a Dose?
If you miss a dose, contact your healthcare provider. Depending on the timing, they may recommend taking the dose later or skipping it entirely. Avoid doubling up on doses.
Where to Get Azstarys at an Affordable Price
If you need help managing the cost of your medications, consider using a prescription discount card like CareCard. These cards can help reduce the out-of-pocket cost of your prescriptions, including brand-name drugs like Azstarys.